Erythritol vs Xylitol:
Which Is Safer for You?
A science-backed, regulation-compliant comparison of two of the most popular sugar alternatives used in sugar-free confectionery today
Erythritol vs Xylitol: The Short Version
Both erythritol and xylitol are sugar alcohols (polyols) used as sweeteners in sugar-free products. Here is what the current evidence shows:
- +Erythritol has virtually zero calories and a glycemic index of 0, with no effect on blood glucose or insulin levels
- +Xylitol provides approximately 2.4 kcal per gram and has a low glycemic index of 7 to 13, significantly lower than regular sugar
- +Both support dental health by inhibiting the bacteria that cause tooth decay
- +Erythritol is generally better tolerated digestively; xylitol can cause more gastrointestinal discomfort at higher doses
- !Recent studies have linked high intake of both sweeteners to temporary changes in platelet activity; further research is ongoing
- !Xylitol is toxic to dogs. Erythritol is not considered a risk to pets at typical dietary exposure levels
- +Both are approved as food additives by the FDA, EFSA, and the WHO/FAO Joint Expert Committee on Food Additives (JECFA)
You are standing in a supermarket aisle, scanning the back of a sugar-free chocolate bar. The ingredient list says "erythritol or xylitol," and suddenly, you are not sure which one you would rather be eating. Both sound technical. Both are marketed as sugar alternatives. But are they equally safe, and which one is actually better suited to your lifestyle?
This guide breaks down the erythritol vs xylitol comparison in full: calories, gut tolerance, dental benefits, cooking behaviour, safety research and how each sweetener is used in products like those across the Diablo Sugar Free range. No scare-mongering, no oversimplification. Just a clear, evidence-based look at two of the most widely used polyols in sugar-free food today.
This article draws on peer-reviewed research from PMC/NCBI, Nature Medicine, Cardiovascular Research (Oxford Academic), and regulatory guidance from the FDA, EFSA, and EU Regulation (EC) No 1924/2006. It is intended for informational purposes. It does not constitute medical advice. Always consult a qualified healthcare professional for personalised dietary guidance.
What Are Erythritol and Xylitol?
Before comparing them, it helps to understand what they actually are. Both erythritol and xylitol belong to the family of compounds known as sugar alcohols, or polyols. Despite the name, they contain no ethanol (the type of alcohol found in drinks). The word "alcohol" refers to their chemical structure, which includes multiple hydroxyl groups.
Sugar alcohols occur naturally in fruits, vegetables and other plants. They are used commercially as low-calorie sweeteners because they taste sweet but are metabolised differently from regular sugar, producing a significantly lower impact on blood glucose. They are found in chewing gum, toothpaste, sugar-free confectionery and baked goods across the world.
What Is Erythritol?
Erythritol is a four-carbon polyol found naturally in small quantities in grapes, watermelons, peaches, mushrooms and fermented foods including wine, beer and soy sauce. Commercially, it is produced through the fermentation of glucose, typically derived from corn or wheat starch.
Its most distinctive property is its absorption profile. Around 90 percent of consumed erythritol is absorbed in the small intestine and then excreted largely unchanged in the urine, meaning it contributes virtually no calories and has essentially no impact on blood glucose or insulin levels. It has been approved for use in foods since 1990 and holds FDA GRAS (Generally Recognised as Safe) status.
What Is Xylitol?
Xylitol is a five-carbon polyol found naturally in small amounts in fruits, vegetables and the fibrous parts of trees. Commercially, it is most often extracted from birch wood or corn cobs and purified for use as a food ingredient.
Unlike erythritol, xylitol is only partially absorbed in the small intestine. The remainder passes to the large intestine where gut bacteria ferment it, which is why high doses can cause digestive discomfort. Xylitol provides around 2.4 kcal per gram compared to 4 kcal per gram for sucrose. It has a low glycemic index of 7 to 13 and is widely used in chewing gums, toothpaste and sugar-free confectionery because it closely mimics the sweetness of sugar.
Erythritol vs Xylitol: Side-by-Side Comparison
| Property | Erythritol | Xylitol | Regular Sugar |
|---|---|---|---|
| Chemical type | 4-carbon polyol | 5-carbon polyol | Disaccharide (sucrose) |
| Calories per gram | ~0 kcal | ~2.4 kcal | 4 kcal |
| Glycemic Index (GI) | 0 | 7 to 13 | 65 to 70 |
| Sweetness vs sugar | 60 to 80% | ~100% | 100% |
| Blood glucose impact | None | Minimal | High |
| Insulin response | None | Minimal | Significant |
| Gut fermentation | Minimal (mostly excreted unchanged) | Significant at higher doses | N/A |
| Digestive tolerance | High (best among polyols) | Moderate; can cause discomfort at higher doses | N/A |
| Dental benefit | Yes (inhibits S. mutans bacteria) | Yes (reduces cavities) | None; promotes decay |
| Safe for dogs? | Not considered harmful at typical dietary levels | No. Toxic to dogs | N/A |
| FDA status | GRAS | GRAS (21 CFR 172.395) | Standard food ingredient |
| Heat stability | Good (stable to ~180 C) | Good (stable to ~200 C) | Good |
| Cooling effect on palate? | Yes, noticeable | Yes, present but milder in baked goods | None |
| Suitable for keto? | Yes (0 net carbs) | Use cautiously (some net carbs) | No |
Sources: FDA GRAS database; JECFA evaluations; PMC absorption studies; OstroVit nutrition analysis. GI values are approximate and may vary by individual response.
Calories and Glycemic Index: Which Impacts Blood Sugar Less?
For anyone watching their sugar intake or following a low-carbohydrate approach, calories and glycemic index are the two numbers that matter most.
Erythritol is the clearer winner on both counts. It provides virtually zero calories and its glycemic index is 0, meaning it triggers no rise in blood glucose and produces no insulin response. For those following a ketogenic diet or closely tracking net carbohydrates, erythritol is typically not counted at all.
Xylitol offers fewer calories than sugar at approximately 2.4 kcal per gram versus 4 kcal per gram for sucrose, but it is not calorie-free. Its glycemic index of 7 to 13 is very low by comparison to table sugar, but not zero. The pancreas does produce a small amount of insulin in response to xylitol, though far less than with regular sugar.
Under Regulation (EC) No 1924/2006, retained in UK law post-Brexit, it is permitted to state that sugar replacers such as xylitol and erythritol produce a lower blood glucose rise after consumption compared to sugar. This claim must be stated in this precise, neutral form and must not be framed as a diabetes management or treatment claim.
Both sweeteners also stimulate the release of gastrointestinal hormones including glucagon-like peptide-1 (GLP-1) and cholecystokinin (CCK), which are associated with satiety signals and slower gastric emptying. This has been explored in research examining their potential relevance to weight management, though no approved weight-loss claims exist for either ingredient under EU or UK food law.
How Are They Digested? Absorption and Gut Tolerance
Digestive tolerance is one of the most practical considerations for everyday consumers, and one area where erythritol and xylitol behave very differently.
Erythritol Side Effects and Digestive Profile
Erythritol is consistently described in the scientific literature as the most digestively friendly of all the major polyols. Because approximately 90 percent of it is absorbed in the small intestine before reaching the colon, there is very little left for gut bacteria to ferment. This significantly reduces the risk of bloating, gas and diarrhoea that are commonly associated with other sugar alcohols including sorbitol and maltitol.
At typical serving sizes found in food products, the vast majority of people tolerate erythritol without any discomfort. At very high doses (generally above 50 g per day), some sensitive individuals may experience nausea or mild abdominal discomfort. Erythritol also does not draw significant water into the intestines through osmosis, which is another reason it is less likely to cause loose stools than other polyols.
Xylitol and Digestive Tolerance
Xylitol is only partially absorbed, with roughly 50 to 75 percent passing through the small intestine and the remainder reaching the large intestine where bacteria ferment it. This fermentation process is what produces the laxative effects commonly associated with sugar alcohols consumed in excess.
For most adults, small to moderate amounts of xylitol (up to around 30 to 40 g per day) are well tolerated. People with greater digestive sensitivity, particularly those with irritable bowel syndrome, may experience discomfort at lower doses. Children may also be more sensitive to its effects than adults.
Under EU Regulation 1169/2011 and its UK equivalent, any food product in which polyols exceed 10 percent of total content must carry the statement: "Excessive consumption may produce laxative effects." This is a legal requirement across the UK and EU, not a product-specific warning. Products containing sweeteners must also carry the statement "with sweetener(s)" alongside the product name.
Dental Health: Which Is Better for Your Teeth?
Both erythritol and xylitol are genuinely beneficial for dental health, and this is one of the most well-established and better-researched areas for both sweeteners.
Regular sugar feeds harmful oral bacteria, particularly Streptococcus mutans, which produce acids that erode tooth enamel and cause cavities. Sugar alcohols do not feed these bacteria in the same way, and both erythritol and xylitol actively interfere with bacterial activity in the mouth.
Xylitol has the longer published track record in dental research and is widely used in toothpastes and chewing gums specifically for its oral health properties. The California Dental Association recommends using xylitol-containing products three to five times daily for a total intake of around 5 grams per day to support dental health.
However, a 2016 literature review published in a peer-reviewed dental journal found that erythritol may outperform xylitol on several key dental metrics. Erythritol effectively reduced dental plaque weight, decreased adherence of S. mutans bacteria to tooth surfaces, inhibited bacterial growth and reduced dental caries more effectively than either xylitol or sorbitol in the studies reviewed.
Under EU and UK food law, the following claim is approved for use with qualifying sweeteners including xylitol: "Xylitol/erythritol contributes to the maintenance of tooth mineralisation." This must be used precisely as approved. It may not be paraphrased or exaggerated.
The 2023 and 2024 Cardiovascular Studies: What You Need to Know
Two high-profile studies have generated significant media coverage in recent years, one focused on erythritol and one on xylitol. Understanding both is essential for a complete and balanced picture, and most competing articles only cover one of them.
The Erythritol Study (Nature Medicine, 2023)
In February 2023, Witkowski, Nemet et al. published a study in Nature Medicine that measured blood erythritol levels in approximately 4,000 patients undergoing cardiovascular assessment at the Cleveland Clinic. Patients with the highest erythritol levels at baseline had a roughly two-fold increased risk of major cardiovascular events compared to those with the lowest levels over a three-year follow-up period. Laboratory experiments also found that erythritol appeared to enhance platelet aggregation in blood samples.
This study has significant and widely acknowledged limitations:
- All participants were already undergoing cardiac assessment, meaning they had elevated baseline cardiovascular risk. The findings may not be generalisable to healthy adults.
- The study observed an association, not a causal relationship. Elevated erythritol in the blood may have been produced endogenously by the body through the pentose phosphate pathway rather than from dietary consumption.
- Dietary erythritol intake was not directly measured. The study could not distinguish between body-produced erythritol and consumed erythritol.
- A Mendelian randomisation analysis, considered a stronger test of causality, did not find a significant link between erythritol and cardiovascular events.
The Xylitol Study (European Heart Journal, 2024)
In 2024, the same research group published a follow-up paper in the European Heart Journal applying a similar methodology to xylitol. They found that elevated plasma xylitol levels were also associated with increased cardiovascular risk markers and appeared to enhance platelet aggregation in a similar manner to erythritol.
This study receives significantly less media attention than the erythritol paper, which creates a misleading impression that erythritol is uniquely problematic. The 2024 data suggests the concern, if confirmed in future research, may be a broader class effect across polyols rather than specific to erythritol.
The Current Scientific Consensus
A comprehensive 2025 review published in Cardiovascular Research (Oxford Academic) concluded that while sugar alcohols have been "implicated in increased cardiovascular risk, a direct causal relationship between their use and cardiovascular events is lacking." The review also noted that Mendelian randomisation trials, which offer stronger causal evidence, do not link sugar alcohols to significant cardiovascular risks.
Current regulatory bodies including the FDA, EFSA and WHO/FAO JECFA continue to classify both erythritol and xylitol as safe for use in foods. Neither has been removed from approved food additive lists. For individuals with existing cardiovascular conditions, discussing sweetener choices with a healthcare professional is a sensible precaution given the evolving nature of this research.
The FDA, EFSA and WHO/FAO JECFA classify both erythritol and xylitol as safe at typical dietary intake levels. The 2023 and 2024 studies are observational in nature and have not established direct causation. Major food safety authorities have not changed their regulatory status in response to these studies. Research is continuing.
Cooking and Baking: Which Performs Better?
If you use these sweeteners at home, their practical baking and cooking properties are just as important as their nutritional profiles.
| Property | Erythritol | Xylitol |
|---|---|---|
| Sweetness vs sugar | 60 to 80% as sweet; use more for equivalent sweetness | Approximately equal; 1:1 substitute |
| Recrystallisation | Re-crystallises when cooled; can make baked goods grainy | More stable; less likely to crystallise |
| Cooling effect | Noticeable cooling sensation on the palate | Cooling effect present but milder in baked goods |
| Browning (Maillard reaction) | Does not brown or caramelise like sugar | Better browning behaviour than erythritol |
| Moisture retention | Draws less moisture; products may be slightly drier | Better moisture retention in finished bakes |
| Heat stability | Stable to approximately 180 C | Stable to approximately 200 C |
| Best applications | Icings, mousses, cold desserts, chocolate coatings | Biscuits, cookies, bread, jams, heated applications |
| 1:1 sugar replacement? | No; adjust quantity and consider a binding agent | Generally yes, with minor recipe tweaks |
Sources: Food science literature; manufacturer technical data. Results may vary by recipe and specific product formulation.
Many commercial sugar-free manufacturers blend erythritol with other sweeteners such as stevia, inulin or steviol glycosides to compensate for erythritol's lower sweetness level and to improve overall texture and mouthfeel in the finished product.
Is Xylitol Safe for Pets?
This is arguably the most important practical safety note in this article. Xylitol is toxic to dogs and potentially other companion animals.
Even small amounts of xylitol can cause life-threatening hypoglycaemia (a rapid and severe drop in blood sugar) and acute liver failure in dogs. The toxic dose is relatively low at approximately 0.1 g per kilogram of body weight for hypoglycaemia. A single piece of xylitol-sweetened chewing gum contains enough xylitol to cause serious harm to a small dog.
Symptoms of xylitol toxicity in dogs include vomiting, loss of coordination, lethargy, weakness and in severe cases seizures and liver failure. If you suspect a dog has consumed any product containing xylitol, contact a veterinarian immediately. Time is critical.
Erythritol is not considered harmful to dogs at the levels typically found in food products. This is a meaningful practical distinction for households with pets when selecting sugar-free products and sweeteners.
Never give xylitol-containing products to dogs. This includes sugar-free chewing gum, certain peanut butters, sugar-free confectionery, some toothpastes and any other product listing xylitol as an ingredient. If in doubt, check the label before sharing any food with a pet.
Which Should You Choose? A Practical Framework
Choose Erythritol If
You want zero calories and zero glycemic impact, you are following a strict keto approach, you have digestive sensitivity, or you have dogs at home and want to minimise household risk.
Choose Xylitol If
You want a 1:1 sugar substitute for baking, you want better browning and moisture in baked goods, or dental health is your primary focus and you do not have pets at risk.
Neither Is Universal
The better choice depends on your specific health goals, digestive tolerance and how you plan to use the sweetener. Speak with a healthcare professional if you have any underlying conditions.
- For zero blood glucose impact: Erythritol is the stronger choice, with a glycemic index of 0 and no insulin response.
- For baking versatility: Xylitol performs closer to sugar in most standard recipes and handles heat better.
- For digestive comfort: Erythritol is better tolerated by most people, particularly at larger amounts.
- For dental health: Both are beneficial. Xylitol has the longer research track record; erythritol shows stronger results in recent comparative studies.
- For households with dogs: Erythritol is the safer choice. Xylitol must be stored securely away from pets at all times.
- For keto and very low-carb diets: Erythritol is typically preferred, as it contributes no net carbohydrates.
Sugar Alcohols in Diablo Sugar Free Products
If you enjoy treats from the Diablo Sugar Free range, you have already been consuming polyols as the primary sweetening system in many of the products. Common sweeteners used across the Diablo range include maltitol, isomalt, sorbitol, and maltitol syrup, alongside other ingredients such as steviol glycosides.
These sweeteners are chosen because they provide sweetness with a lower impact on blood sugar compared to regular sugar, and they allow qualifying products to carry Sugar Free or No Added Sugar designations where applicable under EU and UK food law.
Sugar replacers like those used in the Diablo range produce a lower blood glucose rise after consumption compared to sugar. This is an EFSA-approved nutritional claim that can be used neutrally and precisely.
Diablo Sugar Free products are made with sweeteners instead of sugar, making them a treat for those watching their sugar intake. The full range includes chocolate bars, cookies, wafers, sweets and gummies, spreads and more. All products carry the mandatory "excessive consumption may produce laxative effects" notice in line with UK and EU legal requirements for polyol-containing foods.
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As required by EU Regulation 1169/2011 and its UK equivalent, any Diablo product in which polyols exceed 10 percent of total content carries the mandatory notice: "Excessive consumption may produce laxative effects." This is a standard legal requirement across the category, not unique to the Diablo range, and is designed to help consumers manage their intake.
Frequently Asked Questions
References and Sources
- Witkowski M, Nemet I, et al. (2023). The artificial sweetener erythritol and cardiovascular event risk. Nature Medicine, 29(3), 710-718.
- Witkowski M, et al. (2024). Xylitol is prothrombotic and associated with cardiovascular risk. European Heart Journal.
- Wolnerhanssen B, et al. (2025). Sweeteners: erythritol, xylitol, and cardiovascular risk, friend or foe? Cardiovascular Research. Oxford Academic. DOI: 10.1093/cvr/cvaf091.
- De Cock P. (2016). Erythritol Is More Effective Than Xylitol and Sorbitol in Managing Oral Health Endpoints. Advances in Dental Research, PMC5011233.
- Wolnerhanssen B, et al. (2022). Absorption and Metabolism of the Natural Sweeteners Erythritol and Xylitol in Humans: A Dose-Ranging Study. International Journal of Molecular Sciences. PMC9456049.
- FDA. (2023). An evaluation of the article: The artificial sweetener erythritol and cardiovascular event risk. fda.gov/media/182122.
- NOW Foods. (2025). Erythritol vs. Xylitol: Benefits, Safety, and How They Compare. nowfoods.com.
- EU Regulation (EC) No 1924/2006 on nutrition and health claims made on foods (retained in UK law post-Brexit).
- EU Regulation No 609/2013 on foods for specific groups (excludes the "foods for diabetics" category, which has been prohibited since 2016).
- EU Regulation 1169/2011 on food information to consumers; UK Food Information Regulations 2014.
- Healthline. (2023). Xylitol vs. Erythritol: What's Healthier? healthline.com.
- OstroVit. (2026). Which sweetener is better, erythritol or xylitol? ostrovit.com.
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